A Multivariate Biomarker for Parkinson’s Disease
| dc.contributor.author | Crocetti, Giancarlo | |
| dc.contributor.author | Coakley, Michael | |
| dc.contributor.author | Dressner, Phil | |
| dc.contributor.author | Kellum, Wanda | |
| dc.contributor.author | Lamin, Tamba | |
| dc.date.accessioned | 2025-03-04T11:31:46Z | |
| dc.date.issued | 2015-05-15 | |
| dc.description | In this study, we executed a genomic analysis with the objective of selecting a set of genes (possibly small) that would help in the detection and classification of samples from patients affected by Parkinson Disease. We performed a complete data analysis and during the exploratory phase, we selected a list of differentially expressed genes. Despite their association with the diseased state, we could not use them as a biomarker tool. Therefore, our research was extended to include a multivariate analysis approach resulting in the identification and selection of a group of 20 genes that showed a clear potential in detecting and correctly classify Parkinson Disease samples even in the presence of other neurodegenerative disorders. | |
| dc.description.abstract | In this study, we executed a genomic analysis with the objective of selecting a set of genes (possibly small) that would help in the detection and classification of samples from patients affected by Parkinson Disease. We performed a complete data analysis and during the exploratory phase, we selected a list of differentially expressed genes. Despite their association with the diseased state, we could not use them as a biomarker tool. Therefore, our research was extended to include a multivariate analysis approach resulting in the identification and selection of a group of 20 genes that showed a clear potential in detecting and correctly classify Parkinson Disease samples even in the presence of other neurodegenerative disorders. | |
| dc.identifier.citation | M Coakley, G Crocetti, P Dressner, W Kellum, T Lamin - arXiv preprint arXiv:1505.06967, 2015 | |
| dc.identifier.uri | https://dspace.njala.edu.sl/handle/20.500.144402/129 | |
| dc.language.iso | en_US | |
| dc.publisher | In the Proceedings of 12th Annual Research Day, 2014 - Pace University | |
| dc.title | A Multivariate Biomarker for Parkinson’s Disease | |
| dc.type | Article |