School-wide publications
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Item Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)(BioMed Central, 2016-07-14) Sartelli, MassimoIntra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.Item Saving mothers' lives: things can go wrong.(National Institutes of Health, 1998) Konteh, ROne of the goals of Sierra Leone's primary care programme, established in the 1980s, was to reduce maternal mortality by 30% by the end of the twentieth century, but no significant progress has been made in this direction. The reasons are examined below in the light of a study conducted in one of the country's Chiefdoms.Item A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway(Mary Ann Liebert, Inc., 2017-11-01) Group, Global Alliance for Infections in Surgery WorkingThis declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use of antibiotic agents and antifungal agents in hospitals worldwide especially focusing on surgical infections. As such, it is our intent to raise awareness among healthcare workers and improve antimicrobial prescribing. To facilitate its dissemination, the declaration was translated in different languages.Item The Perfomance of Sierra Leone Youths in the Execution of the Technical Skills of Soccer(2017-12-31) Sesay, Adikali KabaThe development of football in Sierra Leone is dependent upon the availability of players with the tactical, technical and mental capacity to exhibit the appropriate skills and techniques when required. The study focuses on the technical component of the skills and techniques required. Technical ability and technical performance of skills like shooting, heading, passing and dribbling were major components of this research. Youths within the age bracket of 13-18 years were used as respondent or participants to the research. Relevant literatures were reviewed to ascertain how useful they are to the present research. The participants were drawn from all the districts within the country and all the areas of player were also taken into consideration. The stratified and simple random sampling and after the data was collected, the statistical package for social sciences was used to make analysis of the findings. Although age is considered as a factor that will aid players in executing those skills during the research, however, the results proved that different age limit has specific area were they performed better than the other areas.Item SPATIAL VARIATIONS IN INFANT AND CHILD MORTALITY LEVELS IN SIERRA LEONE(2013-11-05) Kandeh, Borbor SamaThe general research objectives of this project were to calculate and map levels of infant, child and adult mortality in the administrative districts of Sierra Leone using 1974 census data, followed by a correlational analysis of these levels with certain key social variables. These were the distribution of medical facilities, the distribution of the population with no formal schooling and malaria endemicity by district. The results showed an estimated infant mortality rate of 215 in 1971 for Sierra Leone. The proportion of children dying before their fifth birthday was pegged at -3582 also for 1971- In relation to other African Countries, Sierra Leone was in the category of countries with very high infant and child mortality levels. Infant and child mortality levels in the administrative areas of Sierra Leone were in general very high but in addition showed some differences in levels. Only the Western Area had an infant mortality rate below 160 in 1971. The highest infant mortality rate was in Pujehun District (272). The pattern is the same when one examines the proportion of children dying before their fifth birthday, with the Western Area having the lowest (.2630) and Pujehun District having the highest (.4431). Attempts at explaining the regional variation in mortality levels by the distribution of health facilities, the percentage of the population with no formal schooling and malaria endemicity failed to provide any significant results once the Western Area was excluded from the analysis.Item Pupils’ Knowledge Level about the Contraindicationsof Cardiovascular Diseases of the HeartlikeDilated Cardiomyopathy (DCM), Hypertensive Heart Disease (HHD) and Pulmonary Heart Disease (PHD) as Health Education Strategy in Preventive Health(2017-07-06) Joseph, Bebeley Samuel**Aim:** The objective of this study was to point out pupils' knowledge level about the contraindications of cardiovascular diseases of the heart like Dilated Cardiomyopathy (DCM), Hypertensive Heart Disease (HHD) and Pulmonary Heart Disease (PHD) as health education strategy in preventive health cased at University Secondary School, Njala.Method: The researcher interviewed mainly high school pupils with a sampled number of one hundred and twenty (n=120).46% (n=55) female and 54% (n=65) male; 67% (n=80) Christians; 33% (n=40) Muslims; were selected using the stratified random sampling.Also stratified were58% (n=70) from the option Pure Science-to-General Science;42% (n=50) from the option Social Science-to-Applied Art; 29.2% (n=35) from SSS(One-to-Two); 70.8% (n=85) from SSS(Three-to-Four);62.8% (n=75) within the age circle of (13-to-17);37.5% (n=45) within the age circle of (18-to-25+) in years.Results: The variables of the finding were tested@ level of significance p < 0.05 through a statistical instrument of T-test.Analysis from the study objective, shows negative skewedness in all three variables as placed in tabulated values (t-scores of-0.802,0.529 and 2.129) of 2, 4 and 6 when tested@p < 0.05.Conclusion: In summing up due to the negative skewedness in all of the variables tested, the finding has demonstrated majority view of high school pupils' low level of knowledge about the contraindications of cardiovascular diseases of the heart as health education strategy in preventive health cased at University Secondary School.The researchers recommend that health education as a teaching subject be included in the schools' curriculum to help in the teaching of preventive health to school pupils.Item The synthesis and defluorination of monofluoroacetate in some Dichapetalum species(Elsevier BV, 1975-02-01) Vickery, BrianItem Use of the FilmArray System for Detection of Zaire ebolavirus in a Small Hospital in Bo, Sierra Leone(American Society for Microbiology, 2015-05-14) Łęski, Tomasz A.Laboratories associated with small hospitals often have limited expertise, personnel, and equipment to rapidly identify rare and emerging infectious diseases. We describe the successful use of the FilmArray system for rapid detection of Ebola virus directly from clinical samples in 6 out of 83 tested subjects in a small health care center in Sierra Leone.